PIMPLE ON LIP TREATMENT
Abstract
Common therapies that are used for the treatment of acne include topical, systemic, hormonal, herbal and combination therapy. Topical applications of erythromycin and clindamycin dosage are used in the treatment of acne.
Keywords
Isotretinoin, clindamycin, sebaceous glands, follicular keratinisation
Introduction
Treatment of acne is the correcting the irregular follicular keratinisation, decreasing the activity of sebaceous glands, decreasing the microbial growth and reducing the inflammation. Common therapies that are used for the treatment of acne include topical, systemic, hormonal, herbal and combination therapy.1
Topical treatment
Topical application of erythromycin and clindamycin dosage (alcoholic solutions, lotions, creams, and gels) on the affected area is effective to control the acne development. A combination of clindamycin and benzoyl peroxide in gel form is better to a topical antibiotic alone.
Systemic treatment
Antibiotics
Oral antibiotics are valuable for moderate to rigorous inflammatory acne characterised by papules, pustules (pimples), nodules and cysts. They are also useful if acne is present in numerous sites like the face and trunk.
Contraceptive pill
Oral contraceptives pill with anti-androgenic characteristic is useful for acne in girls and women.
Isotretinoin
Oral isotretinoin is the therapy of preference for patients who have not satisfactorily responded to oral antibiotics or who present initially with rigorous acne nodules and cysts.
Hormonal
Various drugs are used in the hormonal treatment of acne such as spironolactone, flutamide, cyproterone acetate (block the effect of androgens on the sebaceous gland). Oral contraceptives suppress the ovarian androgen production. Glucocorticoids, suppress the androgen production.
Herbal treatment
Various plant and plant based preparation are used in the treatment of acne such as
Barberry:
The alkaloid berberine extract is use as an anti-inflammatory, antibacterial, and androgen-inhibiting properties.
Brewer’s yeast
Brewer’s yeast exerts is use full as antimicrobial and immune boosting effects and is us in the treatment of systemic acne.
Bittersweet nightshade
It is use as an oral antidote for a various skin problems including acne. Solasodine and soladulcine are the active constituents have anti-inflammatory, astringent, and antimicrobial properties.
Burdock
Burdock is characterized as an alternative and cleansing herb, with antimicrobial and anti-inflammatory effects that may be valuable for acne.
Guggul
Guggul extracts have anti-inflammatory and antibacterial effect that may helpful for acne patients.2,3,4
Conclusion
Therapies that are used for the treatment of acne include topical, systemic, hormonal, herbal and combination therapy.
1.Ray Chanda, Trivedi Poornima, Sharma Vikas. ACNE and Its Treatment Lines. International Journal of Research in Pharmaceutical and Biosciences 2013, 3(1): 1-16.
2.See Jo-Ann. Drug treatment of acne. Australian prescriber Volume 35: Number 6: december 2012.
3.Webster Guy F. Acne vulgaris. BMJ Volume 325 31 August 2002.
4.Ebede Tobechi L, Arch Emily L., Berson Diane. Hormonal Treatment of Acne in Women. J Clin Aesthetic Dermatol. 2009; 2(12):16–22.
